This represents an enormous expansion of CD8 Capital t cells during the febrile phase of dengue disease
This represents an enormous expansion of CD8 Capital t cells during the febrile phase of dengue disease. anti-CD28) but created IFN- by TCR-independent polyclonal stimulation (phorbol 12-myristate 13-acetate [PMA] in addition ionomycin). Therefore, the vast majority of these proliferating, extremely differentiated effector CD8 Capital t cells almost certainly acquire TCR refractoriness during the time the…