Mitochondria were treated with 50 nM tBID or 13 nM tBID alone or in combination with GST-BHRF-1 (0
Mitochondria were treated with 50 nM tBID or 13 nM tBID alone or in combination with GST-BHRF-1 (0.2 was measured by ELISA. of these BH3 domains to antagonize the anti-apoptotic protection afforded by BCL-2 and orthologs. Many and anti-Fas antibody,13,14 irradiation, chemo-therapeutic drugs,15,16 deregulated c-to humans. Viruses seem to have adapted the mechanism of inhibiting…