Blockade of NRP1 reduces infectivity and entry, and alteration of the furin site leads to loss of NRP1 dependence
Blockade of NRP1 reduces infectivity and entry, and alteration of the furin site leads to loss of NRP1 dependence. in order to provide a framework for developing the most appropriate in vitro toolbox to support current and future drug discovery efforts. Introduction Coronaviruses, named for their crown-like spiked surface, are genetically diverse and can infect…