Furthermore, huCD3HET mice were able to mount effective immune responses using two models which tested T cell-dependent responses and functional studies or treatment were anti-human CD3 (Clone OKT3), anti-mouse CD3 (Clone 145-2C11) (BD Biosciences or generated in-house) and anti-mouse TCR (H57-597 from eBiosciences/ThermoFischer)
Furthermore, huCD3HET mice were able to mount effective immune responses using two models which tested T cell-dependent responses and functional studies or treatment were anti-human CD3 (Clone OKT3), anti-mouse CD3 (Clone 145-2C11) (BD Biosciences or generated in-house) and anti-mouse TCR (H57-597 from eBiosciences/ThermoFischer). T cell activation cell cultures Wells were coated overnight at 4C with…